Synapticure’s cover photo
Synapticure

Synapticure

Hospitals and Health Care

Chicago, IL 29,270 followers

The era of personalized care is finally coming to Neurodegenerative disease

About us

Synapticure brings expert virtual care to individuals and caregivers living with neurodegenerative diseases, including Parkinson's, Alzheimer's and related dementia, ALS, and more conditions. Our mission is to democratize access to cutting-edge and personalized care provided by neurologists, mental health providers, and care navigators here for you 24/7.

Website
https://synapticure.com
Industry
Hospitals and Health Care
Company size
51-200 employees
Headquarters
Chicago, IL
Type
Privately Held
Founded
2019
Specialties
GUIDE, Lewy Body, Motor Neuron, Diagnosis, and Medication support

Products

Locations

Employees at Synapticure

Updates

  • Synapticure reposted this

    View profile for Melinda French Gates
    Melinda French Gates Melinda French Gates is an Influencer

    Founder of Pivotal. Co-founder of the Gates Foundation. Author of The Moment of Lift & The Next Day.

    Sometimes, the most innovative solutions can come from people who have lived the problems they’re trying to solve. They see what’s missing, and they care enough to fix it. Sandra Abrevaya and her husband Brian Wallach are perfect examples of this.   On the day they brought their second daughter home from the hospital, they got a call that changed everything: Brian was told he had ALS, and only months to live. After hearing “there’s not much we can do” one too many times, Sandra and Brian decided to build the care they couldn’t find. They founded Synapticure, which offers virtual care to improve the quality of life for patients like Brian, caregivers like Sandra, and families who have been impacted by neurodegenerative disease.   I’m proud to invest in Synapticure. Learn more about its approach—and Sandra and Brian’s touching story: youtu.be/mMJNnvU1pRw

  • Synapticure is excited to share that we will be hosting a webinar on October 28, 2025 with participants in the Neuralink ongoing ALS trial, along with representatives from the company. The webinar will feature Brad Smith, Jake Schneider, and Nick Wray—three individuals with ALS participating in Neuralink’s clinical trials to explore the use of BCI technology in their daily lives. In the webinar we will discuss the technology, the decisions patients make to participate in studies around BCI technology, and connect with patients who have enrolled in the study and are using Neuralink today.  To register for the webinar link below. We hope to see you on the 28th! Register here to attend, ask questions and / or receive the recording. #ALS #BCI https://lnkd.in/gbk-rhfu

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  • Synapticure’s Clinical Research team, led by Abigail O'Connell and Eric Anderson MD PhD MBA FAAN, is excited to join the NEALS Annual Conference next week in Clearwater, Florida October 7-10th! We’re looking forward to connecting with colleagues and collaborators to discuss how Synapticure is expanding remote access to research participation for people living with ALS—helping patients enroll and stay engaged in trials regardless of where they live. We’ll also be presenting a poster with our colleagues at Clene Nanomedicine and Jinsy Andrews: “A Comparison of Baseline Clinical Characteristics Between Decentralized and Institutionally-Enrolled Participants in the CNM-Au8 EAP04 Study” If you’ll be at NEALS, we’d love to connect—whether to discuss partnerships, share insights, or explore how we can work together to bring more inclusive research opportunities to ALS patients everywhere. Reach out to partners@synapticure.com for more information or to schedule a meeting #NEALS #NEALS2025 #ALS #clinicalresearch #DCT #hybridtrials

  • Synapticure reposted this

    We’re proud to share that Synapticure’s R&D lab contributed to a new study from Dr. Sami Barmada’s group at the University of Michigan, published in the Journal of Clinical Investigation. This important work uncovers how a disrupted protein, Nemo-like kinase (NLK), leads to a central hallmark of ALS biology. We are excited to have played a part in this paper. Using our granulin-deficient 3D cortical brain spheroids, a system with these central hallmarks of ALS and FTD biology, Synapticure validated that this protein is elevated consistent with what’s observed in patient tissue. This study highlights the power of our patient-derived brain model platform to: - Recapitulate human disease biology - Validate therapeutic targets emerging from discovery pipelines - Provide a translational bridge between patient data and preclinical development Congratulations to Dr. Barmada, Michael Bekier, Emile Pinarbasi, and all of the authors on this important advance. We’re excited to see our models helping accelerate insights that move the field closer to effective therapies for ALS and related neurodegenerative diseases.

    View profile for Layla Starr

    Neuroscience Ph.D. | Director of Disease Modeling @ Synapticure | neurodegeneration to translation | early-stage biotech builder

    Awesome new paper from Sami Barmada's lab at UMich, whose team continues to push the field forward in unraveling ALS. This work elucidates the role of nemo-like kinase (NLK) in regulating nucleocytoplasmic transport, and shows that elevated NLK directly contributes to TDP-43 mislocalization, emphasizing NLK’s importance as both a driver of disease and promising therapeutic target. The Synapticure lab team and I were glad to contribute to this study using our granulin-deficient 3D brain spheroids, where we observed elevated NLK levels consistent with patient tissue. Congratulations to Sami, Michael, Emile, and the full team on this important advance in ALS research! https://lnkd.in/e-9AaZXP

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  • We’re proud to share that Synapticure’s R&D lab contributed to a new study from Dr. Sami Barmada’s group at the University of Michigan, published in the Journal of Clinical Investigation. This important work uncovers how a disrupted protein, Nemo-like kinase (NLK), leads to a central hallmark of ALS biology. We are excited to have played a part in this paper. Using our granulin-deficient 3D cortical brain spheroids, a system with these central hallmarks of ALS and FTD biology, Synapticure validated that this protein is elevated consistent with what’s observed in patient tissue. This study highlights the power of our patient-derived brain model platform to: - Recapitulate human disease biology - Validate therapeutic targets emerging from discovery pipelines - Provide a translational bridge between patient data and preclinical development Congratulations to Dr. Barmada, Michael Bekier, Emile Pinarbasi, and all of the authors on this important advance. We’re excited to see our models helping accelerate insights that move the field closer to effective therapies for ALS and related neurodegenerative diseases.

    View profile for Layla Starr

    Neuroscience Ph.D. | Director of Disease Modeling @ Synapticure | neurodegeneration to translation | early-stage biotech builder

    Awesome new paper from Sami Barmada's lab at UMich, whose team continues to push the field forward in unraveling ALS. This work elucidates the role of nemo-like kinase (NLK) in regulating nucleocytoplasmic transport, and shows that elevated NLK directly contributes to TDP-43 mislocalization, emphasizing NLK’s importance as both a driver of disease and promising therapeutic target. The Synapticure lab team and I were glad to contribute to this study using our granulin-deficient 3D brain spheroids, where we observed elevated NLK levels consistent with patient tissue. Congratulations to Sami, Michael, Emile, and the full team on this important advance in ALS research! https://lnkd.in/e-9AaZXP

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  • We’re thrilled to share that our CEO & Co-Founder, Sandra Abrevaya, will be a featured keynote speaker at the New York Brain-Computer Interface Symposium (#NYBCI25) on October 3-4 in New York City! Sandra will present “The Power of Advocacy: Driving BCI Forward,” highlighting how patient voices and advocacy guide research, shape policy, and keep people at the center of innovation. We’re honored to be part of this global conversation and can’t wait to share what’s ahead in #neurotech.

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  • Every person living with ALS carries a story of resilience—and every caregiver, a story of love and devotion. At The ALS Association's #ALSNexus conference, we were reminded why this work matters. From our Chief Medical Officer, Dr. Eric Anderson MD PhD MBA FAAN, highlighting the vital role of caregivers, to sharing our work to enable the first fully-remote #ClinicalTrial for #ALS, Synapticure was proud to sponsor and stand alongside a community that refuses to give up on better care, better treatments, and a better future. #ALSCare #Research #Caregiver #Healthcare #Innovation 

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Funding

Synapticure 5 total rounds

Last Round

Series A

US$ 25.0M

See more info on crunchbase