This document discusses statistical power and how it relates to effect size and sample size. It explains that statistical power depends on effect size, sample size, and significance level. Effect size represents the magnitude of the observed effect and can be used to determine the smallest meaningful effect and required sample size. Sample size estimation involves using previous studies to estimate expected effect sizes and perform power analyses to ensure adequate sample sizes can detect meaningful effects. The document emphasizes finding the right balance between effect size and sample size to achieve sufficient statistical power.