How to run python environment through node.js

you can run python virtual environment inside nodejs, you need call python environment from bin directory where you install python virtual environment, and then you can use child_process for run python code inside nodejs, see this example:

const express = require('express')
const app = express()

app.get('/', (req, res) => {

    const { spawn } = require('child_process');
    const pyProg = spawn('~/py3env/bin/python', ['test.py']);

    pyProg.stdout.on('data', function(data) {

        console.log(data.toString());
        res.write(data);
        res.end('end');
    });
})

app.listen(3000, () => console.log('listening on port 3000')) 

even you can excecute command line with shelljs, and in this moment you can run pm2: see this:

const shell = require('shelljs');

shell.exec('pm2 start test.py --interpreter=./py3env/bin/python', function(code, output) {
  console.log('Exit code:', code);
  console.log('Program output:', output);
});

After you setting your python virtual enironment, You can use PythonShell in node js Firstly install PythonShell to your project by this command npm install python-shell --save

then you can call python script in your js file by the following

const path = require('path');
const { PythonShell } = require("python-shell");

// this is your current folder

const py_path = path.join(__dirname, '');

// this is your folder with python environment in it

const python_exe_path = path.join(__dirname, 'python_env/scripts/python.exe'); 


// then create your python shell options

const py_shell_options = {
    mode: 'text',
    pythonPath: python_exe_path,
    pythonOptions: ['-u'], // get print results in real-time
    scriptPath: py_path
    // args: ['value1', 'value2', 'value3']
};

// now you can initialize your shell and ready to use it

const pyshell = new PythonShell('py_scripts/my_script.py', py_shell_options);

// sends a message to the Python script via stdin

pyshell.send('hello');

pyshell.on('message', function (message) {
  // received a message sent from the Python script (a simple "print" statement)
  console.log(message);
});

// end the input stream and allow the process to exit

pyshell.end(function (err,code,signal) {
  if (err) throw err;
  console.log('The exit code was: ' + code);
  console.log('The exit signal was: ' + signal);
  console.log('finished');
});

That it, please read more about PythonShell from the official site