Addressing Challenges In Cross-Functional Collaboration

One of the most underestimated challenges in combination product development is bridging the gap between Pharma and Device teams. Pharma brings deep expertise in clinical pathways, regulatory labeling, and therapeutic outcomes. Device teams, on the other hand, live and breathe design controls, risk analysis, and human factors. Both are essential. But too often, they operate in parallel, not in sync. I've seen projects slow to a crawl because ownership was unclear. Risk files left in limbo. Feedback lost in translation. Not due to lack of talent, but because teams weren’t aligned on what success together looks like. What made the difference for us was intentionally rethinking collaboration. We started bringing Pharma and Device leads into the same conversations early, not just for check-ins but for co-ownership. Shared milestones. Unified risk deliverables. A culture in which asking the other team, “What does this mean?” became second nature. The shift was subtle but powerful: engineers began considering clinical narratives. The pharma team started flagging usability insights. Barriers dissolved. Combination products demand more than technical excellence. They require teams who are willing to cross the aisle and think beyond their functional walls. #CombinationProducts #CrossFunctionalLeadership #MedTech #Pharma #DeviceDesign #HumanFactors #ProductDevelopment #InnovationCulture #injectables 

As I am coaching PMs, I often get the question on how I navigate alignment challenges between cross-functional partners. I spent many years at YouTube building products where safety and user value must coexist. Finding common ground when the stakes are high and opinions diverse felt draining but over time I’ve come to enjoy the process. There is both an art and science to aligning stakeholder. One of the key things I've learned is thinking of alignment at three levels - Problem, Principles, and Product. 1️⃣ Problem - Starting with the Right Question I can't tell you how many times I've been in a room where we've spent hours debating solutions only to realize we weren't even solving the same problem. I remember one particular project where our team had many meetings of increasingly tense discussion before someone finally asked, "Wait, what problem are we trying to solve here?" It was a weird question to ask and felt like we are going backwards. But in that moment we realized how misaligned we were on the problem itself. 2️⃣ Principles - Your North Star in Difficult Terrain Clear principles are non-negotiable, especially for products focused on Safety and Responsibility. They serve as guardrails when you hit those inevitable crossroads where all paths forward involve tough trade-offs. A good way to test whether the principles are written well is to see if they can help answer questions like "Do we delay launch to address this use case? Are we ok to miss the near term opportunity?" 3️⃣ Product - Where the Rubber Meets the Road This is where alignment gets really tested. In my experience, developing options is the secret weapon for driving alignment at the product level. I typically spend hours in 1-1’s trying to understand everyone's perspective before bringing the group together to review options. Something I learned listening to Lenny’s podcast with Ami Vora is that pushback often indicates the other person knows something you don't. So rather than getting defensive, try to approach disagreements as learning opportunities. In evaluating options, I've found that simple pros and cons lists don't help much. Every option will have pros and cons! Instead, I define a few key dimensions that matter based on our product principles and company priorities. Then I grade each option against these dimensions (e.g high/med/low impact). This approach leads to much richer trade-off discussions. It's very rare for one option to be "green" on all dimensions, and that's where the real alignment work happens - deciding what matters most to the company and what you're not willing to compromise on. 👉 Alignment isn't about getting everyone to agree with you. It's about creating a shared understanding of the problem, establishing clear principles, and facilitating informed decisions about the product. Thanks James Beser for coaching me on the art and science of driving Cross-Functional Alignment. Link to the detailed post in my comments.

Cross-functional misalignment is the silent killer of great product strategies. But… how can you fix it? A couple of weeks ago, I asked about the biggest challenge in executing your product strategy, and many of you pointed to cross-functional misalignment. It's a concern that resonates deeply, and it's something we've been addressing with leaders in the CPO Accelerator. Why is this such a common hurdle? Misalignment often stems from the absence of a clear, shared vision. When teams like marketing, sales, and engineering are not aligned with the product vision, efforts become fragmented. This lack of unity can cause delays, wasted resources, and ultimately, products that miss the mark. To effectively tackle this, communication is key. Leaders must articulate the product strategy across all levels, ensuring every team understands how their work contributes to the bigger picture. This isn't a one-time effort but a continuous dialogue. Regular updates, town halls, and aligned roadmaps can keep everyone on the same track. Repetition is key here 🔑 Empowering product leaders with tools and processes to foster alignment is essential. This is where Product Operations can bring immense value, acting as a bridge between teams. By optimizing workflows and facilitating collaboration, Product Ops ensures that everyone moves toward the same goals without stumbling over each other. Remember, alignment doesn't mean micromanaging. It's about providing clarity, setting boundaries, and then trusting your teams to deliver results. Encourage a culture of experimentation and accountability. Allow teams to make decisions aligned with strategic outcomes, not just ticking off feature lists. By focusing on aligning teams with a shared vision and clear objectives, you can transform cross-functional misalignment from a barrier into an opportunity for collaboration and innovation. Let's make strides toward cohesive strategies that drive meaningful outcomes. How are you ensuring alignment in your organization? I'd love to hear your thoughts.