Life Takes Muscle

This #SMAAwarenessMonth, Life Takes Muscle honors the researchers and clinicians striving for more than survival—advancing care that supports muscle where potential remains. Their work aims higher: greater strength, greater function, and greater independence for those living with spinal muscular atrophy (SMA). Visit LifeTakesMuscle.com to hear the voices driving the future of SMA care. #SMA #PatientCare #SMAAwareness #HealthCare

What do points on a motor scale mean for daily life to someone living with spinal muscular atrophy (SMA)? In Episode 7 of the Life Takes Muscle podcast, Diana Castro MD and Dr Crystal Proud discuss how treatment goals in SMA are shifting from surviving to thriving, and why people living with SMA and providers alike are pushing for more. People living with SMA want to reach beyond the expected. Tune in to explore how your colleagues are meeting those desires. https://bit.ly/3FVoGb5 #SMA #HealthCare #PatientCare #SMAAwareness

August is #SMAAwarenessMonth—a time to champion strength, progress, and possibility. Life Takes Muscle is spotlighting muscle strength and motor function as key drivers of independence for people living with spinal muscular atrophy (SMA). Learn more at LifeTakesMuscle.com #SMA #PatientCare #SMAAwareness #HealthCare

Progressive muscle weakness is a clinical hallmark of spinal muscular atrophy (SMA). For people living with the disease, it not only impacts daily life, it steals independence.* It's time to focus on muscle! Learn more here: https://bit.ly/3FQq6Du #PatientCare #HealthCare #SMAAwareness #SMAindependence *Mercuri E, Finkel RS, Muntoni F, et al. Neuromuscul Disord. 2018;28(2):103-115. Wirth B, Mendoza-Ferreira N, Torres-Benito L. In: Sumner CJ, et al, eds: Spinal Disease Mechanisms and Therapy. Elsevier; 2017:191-210. Cruz R, et al. The Voice of the Patient Report for Spinal Muscular Atrophy. 2018. Duong T, et al. BMC Neurol. 2021;21(1):143.

Welcome to Anaheim and Cure SMA! Scholar Rock and Life Takes Muscle are thrilled to join researchers, healthcare professionals, people living with spinal muscular atrophy (SMA), and their families for this gathering of education and awareness building, community and collaboration. Together, we are amplifying the voices of the community. And together, we are working to change the future of SMA. Let’s talk! #PatientCare #HealthCare #SMAAwareness #CureSMA

For insight into the real day-to-day issues faced by people living with spinal muscular atrophy (SMA), we went straight to the source. In this episode of the Life Takes Muscle podcast, host Diana Castro MD speaks with guests Lyza, Doug, and Andrew, all of whom are living with SMA. They share their experiences of progressive muscle weakness, its effect on their ability to perform daily functions—and, by extension, its impact on their independence. Listen to the full episode here: https://bit.ly/3HziaXS #PatientCare #HealthCare #SMAAwareness #SMAindependence

You attend the Cure SMA conference to hear cutting edge research and connect with patients and caregivers. Scholar Rock and Life Takes Muscle are excited to be at this important gathering, to hear what you and other community members have to share, and to be part of the movement to change the future of spinal muscular atrophy (SMA). #PatientCare #SMAAwareness #CureSMA

Myostatin is a naturally occurring protein that inhibits muscle growth—and impeding myostatin signaling can shift the balance from muscle breakdown to muscle growth.* Could new research strategies that inhibit the myostatin pathway be viable for neuromuscular diseases? How could that impact the treatment of spinal muscular atrophy (SMA)? Explore: https://bit.ly/3YgXKZ5 #PatientCare #HealthCare #SMAAwareness *Abati E, et al. Cell Mol Life Sci. 2022;79(7):374; Lee SJ. Immunol Endor Metab Agents Med Chem. 2010;10:183-194; Carnac G, et al. Curr Genomics. 2007;8(7):415-422.

Healthy muscles are built and broken down according to need. Spinal muscular atrophy (SMA) shifts that balance.* SMN deficiency inhibits muscle growth†, causing the progressive loss of muscle and motor function that are hallmarks of SMA. Discover the implications. https://bit.ly/42rwIRf #PatientCare #HealthCare #SMAAwareness *Le Verche V, et al. in Spinal Muscular Atrophy: Disease Mechanisms and Therapy. 2017:341-356. †Jha NN, et al. JCI Insight. 2023;8(18):e171878; Buchthal F, et al. Brain. 1970;93(1):15-30.

Treating neurologists see snapshots of their patients’ lives. But caregivers to those living with spinal muscular atrophy (SMA) see the continued daily impact of progressive muscle weakness. In this episode of the Life Takes Muscle podcast, host Diana Castro MD speaks with Amy, mother to 16-year-old Mckenna; Kevin, father to 10-year-old Bear; and Soraya, a professional caregiver to 23-year-old Lyza, about the remaining unmet needs in SMA, and their hopes for more. Listen to the full episode here: https://bit.ly/3FR6vTs #PatientCare #HealthCare #SMAAwareness