If your work involves formulation, you won’t want to miss our upcoming webinar about the new GPX.2 P-PSD™ module. Learn how you can use it to integrate drug product batch dissolution data into PBBM, and get recommendations on optimization and validation to increase confidence in your formulation strategies. Register now: https://lnkd.in/gHee-2ta
Simulations Plus, Inc.
Software Development
Research Triangle Park, NC 11,709 followers
Where are you in the drug development process? Save resources & get to market faster with our solutions!
About us
Simulations Plus is a leading provider of modeling and simulation software and consulting services supporting drug discovery, development research, and regulatory submissions. We offer solutions that bridge artificial intelligence (AI) and machine learning (ML), physiologically based pharmacokinetics, quantitative systems pharmacology/toxicology, and population PK/PD modeling approaches. Our technology is licensed and applied by major pharmaceutical, biotechnology, chemical, and consumer goods companies, and regulatory agencies worldwide. For more information visit us at www.simulations-plus.com
- Website
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http://www.simulations-plus.com
External link for Simulations Plus, Inc.
- Industry
- Software Development
- Company size
- 201-500 employees
- Headquarters
- Research Triangle Park, NC
- Type
- Public Company
- Founded
- 1996
- Specialties
- Modeling & Simulation Software and Consulting Services, ADME-Tox Screening, Data Mining, Library Design, PBPK/PD Modeling & IVIVCs, Drug-Drug Interactions & Virtual Population Trials, Nonlinear Metabolism/Transport &Metabolite Tracking, PK/PD Modeling and Simulation, PBPK Modeling & Simulation, Drug Development, Regulatory Writing, Quantitative Systems Pharmacology, Clinical Pharmacology, Model-based Drug Discovery & Development, ADMET Property Estimation, QSAR Modeling & Analysis, QSP/QST modeling, On-site Training, Quantitative Systems Toxicology, End-to-End in silico solutions, Pharmacometrics, NCA PK Reporting, Compartmental PK Reporting, Drug-Induced-Liver-Injury , Cloud-based Web Application KIWI, Non-Alcholic Fatty Liver Disease, in vitro Dissolution Method Design, in vitro Permeability, FREE Chemical Sketching Software, and PBTK Modeling & Analysis/Simulation
Locations
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Primary
Get directions
Research Triangle Park, NC 27709, US
Employees at Simulations Plus, Inc.
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Sharlene Evans
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Daniel J. O'Connor, Sr.
Partnering with customers to provide data-driven, AI/ML + MIDD solutions to create better outcomes.
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John K. Paglia, Ph.D., CFA, CPA, NACD.DC
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John DiBella
Partnering with customers to provide data-driven, AI/ML + MIDD solutions to create better outcomes.
Updates
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From belt-out karaoke hits to some impressive dance moves on the floor, we had a blast! Thanks to everyone who joined us at AAPS PharmSci 360! If you couldn’t make it this year, don’t worry—be sure to sign up for our mailing list so you won’t miss the fun next time. https://lnkd.in/grWuNb-5
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Toxicologists today are asked to predict more with fewer animals, tighter timelines, and higher regulatory expectations. That’s exactly where advanced modeling can change the equation. At the ACT Annual Meeting, our team will be at Booth #417 showcasing how we can help you identify potential DILI hazards early in development https://lnkd.in/g8AmvZYH
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Authors of two recent publications independently estimated that utilization of MIDD approaches save an average of 10-14 months of R&D cycle time per development program—equating to an estimated $140-196M in recouped sales revenue per asset. No one can afford to overlook MIDD approaches. Register for Fortrea’s upcoming webinar to hear from industry experts Liang Zhao Zhao, Jill Fiedler-Kelly, Mark Lovern and John Mondick about the evolution of MIDD. https://lnkd.in/gPApEwmY
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How often has a candidate moved into early-phase only to hit formulation or bioavailability issues? What if you could move upstream of that challenge? At our upcoming webinar on Nov 18th, we’ll dive into how PBPK modeling and developability assessment can form a unified framework to address: - solubility/permeability constraints early - route‐of‐delivery choices informed by mechanistic simulation - reduction of empirical iteration and better alignment with human exposure expectations If you model exposure, clearance or formulation impact, this talk is designed to deliver actionable approaches. Register here: https://lnkd.in/gPNEiAcQ
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How can we navigate the vast landscape of chemical space to design molecules with optimized pharmacokinetics? Join Dr. Rafał Bachorz, Senior Principal Applied Scientist, at the AI in Pharma Conference in Poznań, Poland on Tuesday, November 18 at 11:00 AM, for his talk, “Navigating Synthon Space: Property-Driven Molecular Optimization for Pharmacokinetics.” In this session, Rafał will explore how Chemspace Freedom 3.0 and ADMET Predictor®, combined with multi-criteria decision analysis (MCDA), enable property-driven optimization across ultra-large chemical spaces—accelerating the path toward molecules with desired PK profiles. This is a chance to see how AI-driven modeling and simulation are transforming the way we discover and optimize drug candidates. 👉 If you’ll be at the event, don’t miss Rafał’s session. 💡 If you can’t attend, connect with us to learn how our AI-powered platforms can enhance your drug design and development strategies. https://lnkd.in/dVsgcNSd #AIinPharma #DrugDiscovery
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If your work involves formulation, you won’t want to miss our upcoming webinar about the new GPX.2 P-PSD™ module. Learn how you can use it to integrate drug product batch dissolution data into PBBM, and get recommendations on optimization and validation to increase confidence in your formulation strategies. Register now: https://lnkd.in/gHee-2ta
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From karaoke and line dancing to great food and drinks, Rx to Rock: Honky Tonk was an unforgettable night. Thanks to everyone who joined us at AAPS PharmSci 360! Didn't make it? Register for our mailing list so you never miss an invite! https://lnkd.in/grWuNb-5
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Sound check underway at #RXToRock! Join us in Lone Star C on the 2nd floor at the Hyatt tonight for line dancing and karaoke.
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Day 2 at American Association of Pharmaceutical Scientists (AAPS) | @aapscomms is underway! Catch our experts at their poster presentations for a ticket to our #RXToRock after-hours event, featuring live karaoke and line dancing. Can't make the presentations? Come see us in booth #3635 to snag your ticket for tonight!
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