Roche Sequencing USA

Explore our KAPA HyperExome V2 Probes, a new whole-exome sequencing design, which unlocks unique insights in clinical research by capturing more content from key genomic databases. ➡️ Cover more bases & reduce “blind spots,” leaving fewer unknowns ➡️ Increase value & confidence in the results with superior coverage of database content Unlock unique insights: https://spkl.io/6040ADENy #Oncology #NGS #BioPharma #PrecisionMedicine #MRD #CancerResearch #Genomics #DrugDiscovery

At AMP? Don't miss our session at 11:00 a.m. TODAY. Learn how SBX is transforming WGS and enhancing MRD detection. 🗓️ Date: November 12, 2025 ⏰ Time: 11:00–11:50 a.m. EST Room: 151AB, Thomas Menino Convention Center One novel system, many applications: 🧬 WGS for paired tumor-normal samples: in-depth data and workflow presented by Dr. Edwin Cuppen (Hartwig Medical Foundation). 🧬Enhanced ctDNA detection for MRD research: Dr. Mahdi Golkaram (Roche Diagnostics Solutions) will discuss how SBX Duplex Sequencing can increase sequencing throughput, reduce SNP error, and improve ctDNA detection by incorporating methylation features. Visit Booth #511 to see the AXELIOS SBX system in person! View all the Roche events at AMP 🔗 https://spkl.io/6043Aw4QR #Genomics #AMPath2025 #HumanGenetics #RocheSBX #YourSpaceToInnovate The AXELIOS platform, SBX technology and analysis tools are in development and not commercially available. The content of this material reflects current study results and/or design goals. The AXELIOS Platform based on SBX Technology will be launched for Research Use Only. Not for use in diagnostic procedures.

Is NGS part of your Molecular Pathology research? If it is, you won’t want to miss our 11 a.m. session, at AMP, about the novel, high-throughput sequencing by expansion technology (SBX). We’ll cover: 🧬 A novel WGS workflow for paired tumor-normal samples 🧬 Enhanced ctDNA detection for MRD research using SBX-Duplex for high ctDNA signal sensitivity Presenters: Dr. Edwin Cuppen (Hartwig Medical Foundation) and Dr. Mahdi Golkaram (Roche Diagnostics Solutions). View all the Roche events at AMP 🔗 https://spkl.io/6042Aw4aM #Genomics #AMPath2025 #HumanGenetics #RocheSBX #YourSpaceToInnovate The AXELIOS platform, SBX technology and analysis tools are in development and not commercially available. The content of this material reflects current study results and/or design goals. The AXELIOS Platform based on SBX Technology will be launched for Research Use Only. Not for use in diagnostic procedures.

Visit us at AMP and dive into new data from AXELIOS, the novel sequencing by expansion (SBX) technology from Roche–and explore the potential of this versatile, high-throughput solution to transform cancer genomics. Highlights: 📌 WGS for paired tumor-normal samples: Dr. Edwin Cuppen (Hartwig Medical Foundation) will share WGS data and workflow logistics for a new 100-sample study. 📌 Enhanced ctDNA detection for MRD research: Dr. Mahdi Golkaram (Roche Diagnostics Solutions) will discuss how SBX Duplex Sequencing can increase sequencing throughput, reduce SNP error, and improve detection by incorporating methylation features leading to higher ctDNA detection sensitivity. 🗓️ Date: November 12, 2025 ⏰ Time: 11:00–11:50 a.m. EST Room: 151AB, Thomas Menino Convention Center Stop by Booth #511 to see the AXELIOS system in person View all the Roche events at AMP 🔗 https://spkl.io/6042Aw4vk #AMPath2025 #Genomics #HumanGenetics #RocheSBX #YourSpaceToInnovate The AXELIOS platform, SBX technology and analysis tools are in development and not commercially available. The content of this material reflects current study results and/or design goals. The AXELIOS Platform based on SBX Technology will be launched for Research Use Only. Not for use in diagnostic procedures.

Excessive start site bias can lead to uneven coverage and missed variants, forcing costly re-sequencing. Some DNA library prep workflows, like those with tagmentation-based fragmentation, are more prone to this issue. In contrast, the KAPA EvoPlus V2 Kit offers start site patterns that more closely resemble the AT/CG composition of the input DNA, indicating less bias, which can improve data reliability and increase sequencing efficiency. Minimize start site bias🔗 https://spkl.io/6043ATImF #NGS #Genomics #LibraryPrep #Sequencing #Roche For Research Use Only. Not for use in diagnostic procedures.

The KAPA HyperCap Workflow for targeted NGS can help you unmask rare variants with a wide variety of pre-designed and custom panels. Learn how: https://spkl.io/6041AuLRS #DNA #RNA #Genomics #LifeScience #NGS #NextGenSequencing

Struggling with fixed insert sizes in your NGS library prep? Optimize your sequencing resources with the KAPA EvoPlus V2 Kit. Unlike tagmentation-based workflows, our kit provides the flexibility to choose your insert size, enabling you to: 🧬 adjust DNA insert length with time-dependent enzymatic fragmentation, and then ☑️ confirm that the library molecules fall within your target size range through electrophoretic assays Start tuning🔗 https://spkl.io/6048AnFYG tuning_campaign=_DIA-00646-25-P0090 #NGS #Genomics #LibraryPrep #Sequencing #Roche For Research Use Only. Not for use in diagnostic procedures.

🚀 Streamline your NGS panel design! The Roche HyperDesign Online Software Tool uses powerful algorithms to create pre-optimized panels, eliminating further optimization needs and costly trials of design iterations. Learn more by reading the case studies and tech spotlight🔗 https://spkl.io/6047AO28F Case studies show probes designed by Roche HyperDesign Tool have superior performance, with lower Fold 80 base penalty and higher % bases covered ≥ 30X compared to other tools. Start designing your NGS panel for FREE 🔗 https://spkl.io/6048AO282 #TargetEnrichment #NGS #CancerResearch #Biomarkers #PrecisionMedicine #ComprehensiveGenomicsProfiling For Research Use Only. Not for use in diagnostic procedures.

Here’s how to find your space to innovate at the ASHG Annual Meeting! Join us and see how sequencing by expansion (SBX), currently in development, has the potential to shape the future of genomics. #Genomics #ASHG #HumanGenetics #RocheSBX #GenomicsInnovation Dive deeper into SBX 🔗 https://spkl.io/6041AnFYJ

Will we see you at ASHG? We’ll be there! We’re presenting a new workflow for low-pass WGS, which offers a simplified, high-throughput method for human genotyping. 🗓️ Friday Oct 17th, 2:30-4:30 pm 🧬 Poster 4093F: A versatile and streamlined library preparation workflow for low-pass WGS applications. 👩🔬 Presented by Mariana Kiehl This method enables simultaneous, automated processing and sequencing of hgDNA; just 20 M reads per sample yields 1X average coverage with high alignment rate and low artifact rate–without the need for QC prior to library pooling. The results show high alignment and low artifact rates, and the imputed variant calling is highly accurate--with recall greater than 0.92 and precision greater than 0.96. #Genomics #ASHG #NGS #NextGenSequencing